Clinical Tropical Medicine
Staff
Funding
Collaborators
Key Publications
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Lab Head: Dr James McCarthy
James.McCarthy@qimr.edu.au
The focus of the Clinical Tropical Medicine laboratory is to apply modern techniques in microbiology, molecular biology and immunology to study clinical problems associated with infectious diseases in tropical environments.
A particular interest in this laboratory is the study of drug resistance in a range of parasites, and the development of novel diagnostic techniques. Our current projects include:
- Study of drug resistance in human intestinal helmith infections
- Study of diagnostic techniques for detection of drug resistance in helmith infections
- Development of novel diagnostics for intestinal helminth infections
- Study of rapid diagnostic kits for diagnosis of malaria
- Study of the epidemiology of Q fever in Queensland
- Study of the epidemiology of drug resistance in tuberculosis in Papua New Guinea
- Study of drug resistance in human scabies
- Evaluation of novel anti-malarial agents
- Investigation of pathogenic and public health issues related to malaria during pregnancy
Staff
| Labhead: | Dr James McCarthy | James.McCarthy@qimr.edu.au |
| Senior Research Officer: | Dr Kathy Andrews | Kathy.Andrews@qimr.edu.au |
| Research Officer: | Dr Cielo Pasay | Cielo.Pasay@qimr.edu.au |
| Research Assistant: | Mr Lewis Melville | Lewis.Melville@qimr.edu.au |
| PhD scholar: | Mr Alex Sykes | Alex.Sykes@qimr.edu.au |
| Honours students: | Ms June Chia Mr Nelson Lee |
June.Chia@qimr.edu.au Nelson.Lee@qimr.edu.au |
| Visiting scientists: | Dr Wen Lee Ms Yvonne Adams |
Wen.Lee@qimr.edu.au Yvonne.Adams@qimr.edu.au |
Funding
We gratefully acknowledge support from the following organisations and funding bodies:
UNDP / Worldbank / WHO Special Program for Research and Training in Tropical Diseases
National Health and Medical Research Council of Australia
The Australian Research Council
The Australian Centre for International & Tropical Health and Nutririon (ACITHN)
Collaborators
- Professor David Kemp, QIMR
- Dr Katja Fisher, QIMR
- Dr Andrew Kotze, CSIRO, St Lucia, Brisbane
- Dr Glen Coleman, Veterinary School, University of Queensland, St Lucia, Brisbane
- Dr Steven Barker, University of Queensland
- Dr Moses Bokarie, Papua New Guinea Institute for Medical Research, Madang, PNG
- Dr Qin Cheng, Army Malaria Research Institute
- Dr Tony Allworth, Director, Infectious Diseases Unit, Royal Brisbane & Women's Hospital
- Dr Tania Supali, University of Indonesia, Jakarta
- Professor Jerzy Behnke, University of Nottingham
- Dr Adrian Wolstenholme, University of Bath
- Dr Tony Smithyman, CellLabs Pty Limited, Brookvale NSW
- Dr Reinhard Schwartz-Albiez, German Cancer Research Centre (DKFZ), Heidelberg [http://www.hyg.uni-heidelberg.de/sfb544/]
- Professor David Fairlie, IMB, University of Queensland
Key Publications
Kotze, A.C., Coleman, G.T., Mai, A. and McCarthy, J.S. (2005) Field evaluation of anthelmintic drug sensitivity using in vitro egg hatch and larval motility assays with Necator americanus recovered from human clinical isolates. International Journal for Parasitology 35: 445-453.
McCarthy, J.S. (2005) Malaria chemoprophylaxis: in war and peace. Medical Journal of Australia 182: 148-149.
Currie, B.J. and McCarthy, J.S. (2005) Strongyloides stercoralis infection as a manifestation of immune restoration syndrome? Clinical Infectious Diseases 40: 635.
McCarthy, J.S., Kemp, D.J., Walton, S.F. and Currie, B.J. (2004) Scabies: more than an irritation. Postgraduate Medical Journal 80: 382-387.
Geraghty, C.M. and McCarthy, J.S. (2004) Japanese encephalitis vaccine: is it being sufficiently used in travellers? Medical Journal of Australia 181: 269-270.
Skinner-Adams, T.S., McCarthy, J.S., Gardiner, D.L., Hilton, P.M. and Andrews, K.T. (2004) Antiretrovirals as antimalarial agents. Journal of Infectious Diseases 190: 1998-2000.
Kotze, A.C., Clifford, S., O'Grady, J., Behnke, J.M. and McCarthy, J.S. (2004) An in vitro larval motility assay to determine anthelmintic sensitivity for human hookworm and Strongyloides species. American Journal of Tropical Medicine and Hygiene 71: 608-616.
Wu, Y., Egerton, G., McCarthy, J.S., Nutman, T.B. and Bianco, A.E. (2003) Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1. Filaria Journal 2: 6.
McCarthy, J.S., Wieseman, M., Tropea, J., Kaslow, D., Abraham, D., Lustigman, S., Tuan, R., Guderian, R.H. and Nutman, T.B. (2002) Ochocerca volvulus glycolytic enzyme fructose-1, 6-biphosphate aldolase as a target for a protective immune response in humans. Infection and Immunity 70: 851-858.
McCarthy JS, Weisman M, Tropea J, Kaslow D, Tuan R and Nutman TB. (2002) Fructose bisphosphate aldolase: a major antigen in human Onchocerca volvulus infection. Infection and Immunity 70(2):851-8.
McCarthy JS and Garrow SC. Parasite elimination programs: at home and away (Editorial). (2002) Medical Journal of Australia 176 (10):456-457.
McCarthy JS, Peacock D, Trown K, Bade P, Petri W and Currie B. (2002) Endemic invasive amoebiasis in northern Australia. Medical Journal of Australia 177(10):570.