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Johnson BJ, Le TT, Dobbin CA, Banovic T, Howard CB, Leon Flores FD, Vanags D, Naylor DJ, Hill GR, Suhrbier A . Heat shock protein 10 Inhibits lipopolysaccharide-induced inflammatory mediator production.
J Biol Chem. 2005. 280(6):4037-47 Prov 13432AU
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Ogbourne SM, Suhrbier A , Jones B, Cozzi SJ, Boyle GM, Morris M, McAlpine D, Johns J, Scott TM, Sutherland KP, Gardner JM, Le TT, Lenarczyk A, Aylward JH, Parsons PG. Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. Cancer Res. 2004 Apr 15;64(8):2833- 9. PCT/AU01/00678-80 |
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NY-ESO-1
ISCOM
Vaccine |
Maraskovsky E, Sjolander S, Drane DP, Schnurr M, Le TT, Mateo L, Luft T, Masterman KA, Tai TY, Chen Q, Green S, Sjolander A, Pearse MJ, Lemonnier FA, Chen W, Cebon J, Suhrbier A . NY-ESO-1 protein formulated in ISCOMATRIX adjuvant is a potent anticancer vaccine inducing both humoral and CD8+ T-cell- mediated immunity and protection against NY-ESO-1+ tumors. Clin Cancer Res. 2004. 10(8):2879-90. WO0048630 |
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Kunjin Replicons
Vaccine |
Anraku I, Harvey TJ, Linedale R, Gardner J, Harrich D, Suhrbier A , Khromykh AA. Kunjin virus replicon vaccine vectors induce protective CD8+ T-cell immunity. J Virol. 2002 Apr;76(8):3791-9. PCT/AU02/01598
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RepliKun Ltd 2005
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Pam2Cys Peptides
Vaccine |
Jackson DC, Lau YF, Le T, Suhrbier A , Deliyannis G, Cheers C, Smith C, Zeng W, Brown LE. A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses. Proc Natl Acad Sci U S A. 2004. 101(43):15440-5.
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Suhrbier A. Polytope vaccines for the codelivery of multiple CD8 T-cell epitopes. Expert Rev Vaccines. 2002 Aug;1(2):207-13. WO9524925
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