Molecular Cancer Epidemiology

Group Leader

Associate Professor Amanda Spurdle

Summary

The Molecular Cancer Epidemiology Laboratory studies breast and ovarian cancer, endometrial cancer, colon cancer and prostate cancer, with a focus on identifying molecular signatures of normal and tumour tissue that can point to the genetic and environmental causes of these cancers. The laboratory covers a range of projects with the themes of cancer epidemiology and molecular pathology.

Conditions researched

Current research

Staff

Group Leader: Associate Professor Amanda Spurdle

Postdoctoral staff: Dr Jodie Painter, Dr Felicity Lose, Dr Tracy O’Mara, Dr Jyotsna Batra

Research Assistants: Michael Parsons, Alex Metcalf

PhD students: Bryony Thompson, Yen Tan, SriLakshmi Srinivasan

Funding

We gratefully acknowledge support from the following organisations and funding bodies:

  • National Health and Medical Research Council
  • Cancer Australia

Collaborators

ANECS (Australian National Endometrial Cancer Study)

ENIGMA consortium (Evidence-based Network for the Interpretation of Germline Mutant Alleles)

InSiGHT (International Society for Gastrointestinal Hereditary Tumours Incorporated)

Colon Cancer Family Registry

kConFab (Kathleen Cuningham Foundation consortium for research into familial breast cancer)

BCAC consortium (Breast Cancer Association Consortium)

CIMBA consortium (Consortium of Investigators of Modifiers of BRCA1/2)

E2C2 (Epidemiology of Endometrial Cancer Consortium)

PRACTICAL consortium (Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome)

Professor Douglas Easton, Dr Alison Dunning and Professor Paul Pharoah, Cambridge University, UK

Professor David Goldgar and Associate Professor Sean Tavtigian, University of Utah, USA

Professor Fergus Couch, Mayo Clinic College of Medicine, USA

Professor Ian Tomlinson, University of Oxford, UK

Professor Xiao-Ou Shu, VanderBilt University, USA

Dr Logan Walker, University of Otago, New Zealand

Professor Melissa Brown, Prof Lakhani, University of Queensland

Professor Judith Clements, Queensland University of Technology

Dr Andreas Obermair, Royal Brisbane and Women's Hospital

Dr Jermaine Coward, Mater Medical Research Institute, Australia

Professor Georgia Chenevix-Trench, Cancer Genetics, QIMR

Dr Penny Webb and Dr Christina Nagle, Gynaecological Cancer Group, QIMR

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