Immunovirology - key publications - Queensland Institute of Medical Research

Fros JJ, Liu WJ, Prow NA, Geertsema C, Ligtenberg M, Vanlandingham DL, Schnettler E, Vlak JM, Suhrbier A, Khromykh AA, Pijlman GP. Chikungunya Virus Nonstructural Protein 2 Inhibits Type I/II Interferon-Stimulated JAK-STAT Signaling. Journal of Virology. 2010;84(20):10877-10887.

Gardner J, Anraku I, Le TT, Larcher T, Major L, Roques P, Schroder WA, Higgs S, Suhrbier A. Chikungunya Virus Arthritis in Adult Wild-Type Mice. Journal of Virology. 2010;84(16):8021-8032.

Lidbury BA, Rulli NE, Musso CM, Cossetto SB, Zaid A, Suhrbier A, Rothenfluh HS, Rolph MS, Mahalingam S. Identification and Characterization of a Ross River Virus Variant That Grows Persistently in Macrophages, Shows Altered Disease Kinetics in a Mouse Model, and Exhibits Resistance to Type I Interferon. Journal of Virology. 2011;85(11):5651-5663.

Major L, Schroder WA, Gardner J, Fish RJ, Suhrbier A. Human papilloma virus transformed CaSki cells constitutively express high levels of functional SerpinB2. Experimental Cell Research. 2011;317(3):338-347.

Ramsay JR, Suhrbier A, Aylward JH, Ogbourne S, Cozzi SJ, Poulsen MG, Baumann KC, Welburn P, Redlich GL, Parsons PG. The sap from Euphorbia peplus is effective against human nonmelanoma skin cancers. British Journal of Dermatology. 2011;164(3):633-636.

Rattanasena P, Anraku I, Gardner J, Le TT, Wang XJ, Khromykh AA, Suhrbier A. Prime-boost vaccinations using recombinant flavivirus replicon and vaccinia virus vaccines: an ELISPOT analysis. Immunol Cell Biol. 2011;89(3):426-36.

Schroder WA, Major L, Suhrbier A. The Role of SerpinB2 in Immunity. Critical Reviews In Immunology. 2011;31(1):15-30.

Schroder WA, Gardner J, Le TT, Duke M, Burke ML, Jones MK, McManus DP, Suhrbier A. SerpinB2 deficiency modulates Th1/Th2 responses after schistosome infection. Parasite Immunology. 2010;32(11-12):764-768.

Wang D, Suhrbier A, Penn-Nicholson A, Woraratanadharm J, Gardner J, Luo M, Le TT, Anraku I, Sakalian M, Einfeld D, Dong JY. A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis. Vaccine. 2011;29(15):2803-2809.

Chang DC, Liu WJ, Anraku I, Clark DC, Pollitt CC, Suhrbier A, Hall RA, Khromykh AA.Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virus.Nat Biotechnol. 2008 Apr 20; [Epub ahead of print] [pubmed abstract]

Elliott SL, Suhrbier A, Miles JJ, Lawrence G, Pye SJ, Le TT, Rosenstengel A, Nguyen T, Allworth A, Burrows SR, Cox J, Pye D, Moss DJ, Bharadwaj M. Phase I trial of a CD8+ T-cell peptide epitope-based vaccine for infectious mononucleosis. J Virol. 2008 Feb;82(3):1448-57. [pubmed abstract]

Challacombe JM, Suhrbier A, Parsons PG, Jones B, Hampson P, Kavanagh D, Rainger GE, Morris M, Lord JM, Hoang-Le D,Le TTT, and Ogbourne SM. Neutrophils are a key component of the anti-tumor efficacy of topical chemotherapy with 3-ingenyl angelate. J Immunol 177(11):8123-32. [pubmed abstract]

Darnell GA, Schroder WA, Gardner J, Harrich D, Yu H, Antalis TA, Medcalf RL, Warrilow D and Suhrbier A. 2006. SerpinB2 is an inducible host factor involved in enhancing HIV-1 transcription and replication. J Biol Chem 281(42):31348-58. [pubmed abstract]

Pijlman GP, Suhrbier A, Khromykh AA. 2006. Kunjin virus replicons: an RNA-based, non-cytopathic viral vector system for protein production, vaccine and gene therapy applications. Expert Opin Biol Ther 6(2):135-45. [pubmed abstract]

Johnson BJ, Le TT, Dobbin CA, Banovic T, Howard CB, Flores Fde M, Vanags D, Naylor DJ, Hill GR, Shurbier A. Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production. J Biol Chem. 2005 Feb 11;280(6):4037-47. [pubmed abstract]

Ogbourne SM, Suhrbier A, Jones B, Cozzi SJ, Boyle GM, Morris M, McAlpine D, Johns J, Scott TM, Sutherland KP, Gardner JM, Le TT, Lenarczyk A, Aylward JH, Parsons PG. Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. Cancer Res. 2004 Apr 15;64(8):2833-9. [pubmed abstract]

Suhrbier A, La Linn M. Suppression of antiviral responses by antibody-dependent enhancement of macrophage infection. Trends Immunol. 2003 Apr; 24(4): 165-8 [pubmed abstract]

Darnell GA, Antalis TM, Johnstone RW, Stringer BW, Ogbourne SM, Harrich D, Suhrbier A. Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motif. Mol Cell Biol. 2003 Sep; 23(18): 6520-32 [pubmed abstract]

Harvey TJ, Anraku I, Linedale R, Harrich D, Mackenzie J, Suhrbier A, Khromykh AA. Kunjin virus replicon vectors for human immunodeficiency virus vaccine development. J Virol. 2003 Jul; 77(14): 7796-803 [pubmed abstract]

Woodberry T, Gardner J, Elliott SL, Leyrer S, Purdie DM, Chaplin P, Suhrbier A. Prime boost vaccination strategies: CD8 T cell numbers, protection, and Th1 bias. J Immunol. 2003 Mar 1; 170(5): 2599-604 [pubmed abstract]

A. D. Mylonas, A. M. Brown, T. L. Carthew, B. McGrath, D. M. Purdie, N. Pandeya, P. C. Vecchio, L. G. Collins, I. D. Gardner, F. J. DeLooze, E. Reymond, A. Suhrbier. 2002. The natural history of Ross River virus induced epidemic polyarthritis. Med J Aust. 177; 356-360 [pubmed abstract]

May La Linn, J. Gardner, D. Warrilow, G. A. Darnell, C. R. McMahon, I. Field, A. D. Hyatt, R. W. Slade, A. Suhrbier 2001. An arbovirus of marine mammals; a new alphavirus isolated from the elephant seal louse, Lepidophthirus macrorhini. J. Virol. 75: 4103-9 [pubmed abstract]

A.D. Hislop, M.F. Good, L. Mateo, J. Gardner, M.H. Gatei, R.C.W. Daniel, B.V. Meyers, M.F. Lavin and A. Suhrbier. 1998. Vaccine-induced cytotoxic T lymphocytes protect against retroviral challenge. Nature Medicine 4 (10);1193 - 1196 [pubmed abstract]

T.M. Antalis, May La Linn, K. Donnan, L. Mateo, J. Gardner, J.L. Dickinson, K. Buttigieg and A. Suhrbier. 1998. The serpin Plasminogen Activation Inhibitor Type-2 protects against viral cytopathic effects by constitutive interferon ab priming. J. Exp. Med. 187:1799-1811 [pubmed abstract]

S. Thomson, R. Khanna, J. Gardner, S. R. Burrows, B. Coupar, D. J. Moss, A. Suhrbier. 1995. Minimal epitopes expressed in a recombinant polyepitope protein are processed and presented to CD8+ cytotoxic T cells: Implications for vaccine design. PNAS USA 92; 5845-5849 [pubmed abstract]

Suhrbier A, La Linn M. Suppression of antiviral responses by antibody-dependent enhancement of macrophage infection. Trends Immunol. 2003 Apr; 24(4): 165-8 [pubmed abstract]