- Home
- About Us
- Our Research
- Support Us
- Students
- News & Events
- Careers
- Contact Us
- QSkin
- CMV study
- Queensland Pancreatic Cancer Study
- Australian Centre for Vaccine Development
| Tweet |
About our study
The Genetics of Serrated Neoplasia (GSN) project started in Brisbane in 2005 and is now a collaborative project with investigators in Australia, New Zealand, Canada, the United States, Sweden and the United Kingdom. The project has currently enrolled over 200 patients with advanced or multiple serrated polyps and their families.The project is funded from a United States Government-based research body, as well as from Cancer Council Queensland. Activities are directed towards recognition of families and individuals with serrated neoplasia, understanding the nature of the condition, and preventing colorectal cancer in both patients and their relatives through the identification of risk factors and genetic backgrounds.
The project conducts polyp and cancer characterisation through immunohistochemistry, molecular analysis and pathology review, family pedigree analysis, linkage and association studies, lifestyle risk factor analysis and candidate gene sequencing. The two main conditions studied are hyperplastic polyposis (HPS) and familial serrated neoplasia (Jass syndrome).